Ionic current abnormalities associated with prolonged action potentials in cardiomyocytes from diseased human right ventricles.

@article{Li2004IonicCA,
  title={Ionic current abnormalities associated with prolonged action potentials in cardiomyocytes from diseased human right ventricles.},
  author={Gui-Rong Li and Chu-pak Lau and T H Leung and Stanley Nattel},
  journal={Heart rhythm},
  year={2004},
  volume={1 4},
  pages={460-8}
}
OBJECTIVES This study was designed to determine whether ionic currents in right ventricular myocytes from explanted human transplant recipient hearts are related to right ventricular histopathology and function. BACKGROUND Cardiac action potential duration (APD) is prolonged in ventricular tissues/cells from patients with heart failure, but the ionic mechanisms are not well documented. METHODS Membrane currents and transmembrane action potentials in myocytes from right ventricular… CONTINUE READING

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