Ionic channels induced by surfactin in planar lipid bilayer membranes.

@article{Sheppard1991IonicCI,
  title={Ionic channels induced by surfactin in planar lipid bilayer membranes.},
  author={John D. Sheppard and Catherine Jumarie and David G. Cooper and Raynald Laprade},
  journal={Biochimica et biophysica acta},
  year={1991},
  volume={1064 1},
  pages={13-23}
}
Surfactin is a lipopeptide produced by certain strains of Bacillus subtilis and has potent surface activity. Here, we present the first results showing that ion-conducting pores can be formed by surfactin in artificial lipid membranes. With a low aqueous concentration of surfactin (1 microM) and a restricted membrane area (5.10(-5) cm2) we observed conductance jumps that indicate the formation of individual ionic channels in the presence of K+, Rb+, Cs+, Na+ or Li+ chlorides. Although for every… CONTINUE READING