Ionic and osmotic equilibria of human red blood cells treated with nystatin

@article{Freedman1979IonicAO,
  title={Ionic and osmotic equilibria of human red blood cells treated with nystatin},
  author={Jeffrey C. Freedman and Joseph F. Hoffman},
  journal={The Journal of General Physiology},
  year={1979},
  volume={74},
  pages={157 - 185}
}
Human red blood cells have been incubated in the presence of nystatin, which allows Na and K, as well as Cl and pH to equilibrate rapidly when cell volume is set with external impermeant sucrose. The intracellular mean ionic activity coefficients, relative to values in the extracellular solution, for KCl and NaCl are 1.01 +/- 0.02 and 0.99 +/- 0.02 (SD, n = 10), respectively, and are independent of external pH, pH o, and of [sucrose]o. With nystatin the dependence of red cell volume on [sucrose… CONTINUE READING

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Nonsolvcnt water in human crythrocytes

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