Ion-selective formation of a guanine quadruplex on DNA origami structures.

@article{Olejko2015IonselectiveFO,
  title={Ion-selective formation of a guanine quadruplex on DNA origami structures.},
  author={Lydia Olejko and Piotr J. Cywiński and Ilko Bald},
  journal={Angewandte Chemie},
  year={2015},
  volume={54 2},
  pages={673-7}
}
DNA origami nanostructures are a versatile tool that can be used to arrange functionalities with high local control to study molecular processes at a single-molecule level. Here, we demonstrate that DNA origami substrates can be used to suppress the formation of specific guanine (G) quadruplex structures from telomeric DNA. The folding of telomeres into G-quadruplex structures in the presence of monovalent cations (e.g. Na(+) and K(+)) is currently used for the detection of K(+) ions, however… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 3 times. VIEW TWEETS