Ion permeation mechanism of the potassium channel

@article{qvist2000IonPM,
  title={Ion permeation mechanism of the potassium channel},
  author={Johan {\AA}qvist and Victor B. Luzhkov},
  journal={Nature},
  year={2000},
  volume={404},
  pages={881-884}
}
Ion-selective channels enable the specific permeation of ions through cell membranes and provide the basis of several important biological functions; for example, electric signalling in the nervous system. Although a large amount of electrophysiological data is available, the molecular mechanisms by which these channels can mediate ion transport remain a significant unsolved problem. With the recently determined crystal structure of the representative K+ channel (KcsA) from Streptomyces… CONTINUE READING