Ion channels in axon and Schwann cell membranes at paranodes of mammalian myelinated fibers studied with patch clamp.

@article{Wilson1990IonCI,
  title={Ion channels in axon and Schwann cell membranes at paranodes of mammalian myelinated fibers studied with patch clamp.},
  author={Gisela F. Wilson and Shing Yan Chiu},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1990},
  volume={10 10},
  pages={
          3263-74
        }
}
While recent studies have established the presence of voltage-gated ion channels on Schwann cells in culture and on freshly isolated fibers from mature mammals, an important issue not yet explored is whether Schwann cell channels are regionally specialized. In the nodal region, the intimate association between the Schwann cell and its axon suggests that this is a likely site for functional specialization. Here, we examine whether there is a localized expression of channels in the Schwann cell… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 47 REFERENCES

Potassium channel regulation in Schwann cells during early developmental myelinogenesis.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 1990
VIEW 22 EXCERPTS
HIGHLY INFLUENTIAL

Ion channels in vertebrate glia.

  • Annual review of neuroscience
  • 1990
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Na currents and action ootentials in rat myelinated nerve fib & s at 20 and 37 ° C

G Eikhof
  • Pfluegers Arch
  • 1987
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Single-channel recording in myelinated nerve fibers reveals one type of Na channel but different K channels.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 1989
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

Sodium currents in axon-associated Schwann cells from adult rabbits.

  • The Journal of physiology
  • 1987
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

The role of notassium channels in Schwann Schwann

GF Chiu SY. Wilson
  • 1989
VIEW 1 EXCERPT

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