Ion channels are linked to differentiation in keratinocytes

@article{Mauro2004IonCA,
  title={Ion channels are linked to differentiation in keratinocytes},
  author={Theodora M. Mauro and Roslyn Rivkah Isseroff and R M Lasarow and Pamela A. Pappone},
  journal={The Journal of Membrane Biology},
  year={2004},
  volume={132},
  pages={201-209}
}
SummaryIn vivo and in vitro, keratinocyte differentiation is linked with increased extracellular Ca2+. In order to correlate ion channels with cell differentiation and investigate keratinocyte membrane responses to Ca2+, keratinocyte single channel currents were studied using the patch-clamp technique. The most frequently observed channel was a 14 pS nonspecific cation channel. This channel was permeable to Ca2+ and activated by physiological concentrations of Ca2+. We also found a 35 pS Cl… 

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