Ion channels and calcium signaling in cerebral arteries following subarachnoid hemorrhage.

@article{Wellman2006IonCA,
  title={Ion channels and calcium signaling in cerebral arteries following subarachnoid hemorrhage.},
  author={George C. Wellman},
  journal={Neurological research},
  year={2006},
  volume={28 7},
  pages={690-702}
}
Entry of Ca(2+) through voltage-dependent calcium channels (VDCCs) is critical to the regulation of intracellular free calcium concentration ([Ca(2+)](i)) in vascular smooth muscle and thus the control of cerebral artery diameter. Increased VDCC activity in cerebral artery myocytes may contribute to decreased cerebral blood flow and the accompanying neurological deficits associated with subarachnoid hemorrhage (SAH). This review will focus on the impact of SAH on VDCCs and K(+)-selective ion… CONTINUE READING