Ion channels: recent progress and prospects

@article{Chung2002IonCR,
  title={Ion channels: recent progress and prospects},
  author={Shin-Ho Chung and Serdar Kuyucak},
  journal={European Biophysics Journal},
  year={2002},
  volume={31},
  pages={283-293}
}
Determination of the crystal structure of the KcsA potassium channel and its subsequent refinement at 2 Å resolution have stimulated much interest in modelling of ion channels. Here we review the recent developments in ion channels research, focusing especially on the question of structure-function relationships, and discuss how permeation models based on Brownian and molecular dynamics simulations can be used fruitfully in this endeavour. 
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