Ion channel organization of the myelinated fiber

  title={Ion channel organization of the myelinated fiber},
  author={J Andrew Black and Jeffery D Kocsis and Stephen G. Waxman},
  journal={Trends in Neurosciences},
The myelinated axon provides a model in which it is possible to examine how various types of ion channels are incorporated into a membrane to form an excitable neuronal process. The available evidence now indicates that mammalian myelinated fibers contain a repertoire of physiologically active membrane molecules including at least four types of ion channels and an electrogenic Na+,K(+)-pump. Physiological properties of myelinated fibers reflect the distribution of these various types of… CONTINUE READING

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