Ion channel enzyme in an oscillating electric field

  title={Ion channel enzyme in an oscillating electric field},
  author={Vladislav S. Markin and Daosheng Liu and Jan Gimsa and Renate Strobel and Murray D. Rosenberg and Tian Yow Tsong},
  journal={The Journal of Membrane Biology},
To explain the electrical activation of several membrane ATPases, an electroconformational coupling (ECC) model has previously been proposed. The model explained many features of experimental data but failed to reproduce a window of the field intensity for the stimulated activity. It is shown here that if the affinities of the ion for the two conformational states of the transporter (one with binding site on the left side and the other on the right side of the membrane) are dependent on the… CONTINUE READING