Ion-channel Regulation of Chondrocyte Matrix Synthesis in 3D Culture Under Static and Dynamic Compression

@article{Mouw2007IonchannelRO,
  title={Ion-channel Regulation of Chondrocyte Matrix Synthesis in 3D Culture Under Static and Dynamic Compression},
  author={Janna K. Mouw and Stacy M. Imler and Marc E. Levenston},
  journal={Biomechanics and Modeling in Mechanobiology},
  year={2007},
  volume={6},
  pages={33-41}
}
Inhibition of various ion channels alters chondrocyte mechanotransduction in monolayer, but the mechanisms involved in chondrocyte mechanotransduction in three- dimensional culture remain unclear. The objective of this study was to investigate the effects of inhibiting putative ion-channel influenced mechanotransduction mechanisms on the chondrocyte responses to static and dynamic compression in three-dimensional culture. Bovine articular cartilage explants were used to investigate the dose… 
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