Ion Transport in Isolated Rabbit Ileum : II. The interaction between active sodium and active sugar transport

@article{Schultz1964IonTI,
  title={Ion Transport in Isolated Rabbit Ileum : II. The interaction between active sodium and active sugar transport},
  author={Stanley G. Schultz and Ralph Zalusky},
  journal={The Journal of General Physiology},
  year={1964},
  volume={47},
  pages={1043-1059}
}
The addition of actively transported sugars to the solution bathing the mucosal surface of an in vitro preparation of distal rabbit ileum results in a rapid increase in the transmural potential difference, the short-circuit current, and the rate of active Na transport from mucosa to serosa. These effects are dependent upon the active transport of the sugar per se and are independent of the metabolic fate of the transported sugar. Furthermore, they are inhibited both by low concentrations of… 
Sodium and Sugar Fluxes across the Mucosal Border of Rabbit Ileum
TLDR
A model has been developed for the sugar transport system involving a transport site that combines with both sugar and Na and at all Na concentrations tested, there was a 1 : 1 ratio between sugar influx and the sugardependent Na influx.
Sodium and Sugar Fluxes across the Mucosal Border of Rabbit Ileum
TLDR
A model has been developed for the sugar transport system involving a transport site that combines with both sugar and Na and there appeared to be little mediated entry of 3 MG into the cells from Na-free solution.
Electrical properties and active solute transport in rat small intestine
TLDR
It was concluded that an actively transported solute induced not only a depolarization of the mucosal (brush border) membrane but also a hyperpolarized of the serosal (baso-lateral) membrane of an epithelial cell, so that the origin of solute-inducedPDt changes should be attributed to changes in emf's at both membranes.
Interpretation of Hexose-dependent Electrical Potential Differences in Small Intestine
TLDR
The authors have concluded that the “galactose dependent potential is unaffected by sodium concentration but is reduced by increasing potassium concentration”, and have shown that the increase in the Isc across rabbit ileum is a function of both sugar and sodium concentrations in the bathing solution.
The Transport of Salt and Water across Isolated Rat Ileum
  • T. Clarkson
  • Biology
    The Journal of general physiology
  • 1967
TLDR
The aim was to give the simplest possible description, that is to postulate the least number of active transport processes and the most number of separate pathways across the intestine, which was consistent with the following picture of the intestine.
Sodium-coupled amino acid and sugar transport byNecturus small intestine
TLDR
The results of these studies indicate that the Na-coupled mechanisms that mediate the entry of sugars and amino acids across the apical membrane are “rheogenic” (conductive) and result in a decrease in Rm and a depolarization ofψms; and the subsequent increase in (Rm/Rs) and repolarizations are the results of a decrease at the basolateral membrane.
Sodium-dependent sugar transport in the intestine.
  • A. Goldner
  • Biology
    Metabolism: clinical and experimental
  • 1973
...
...