Ion Transport in Confined Geometries below the Nanoscale: Access Resistance Dominates Protein Channel Conductance in Diluted Solutions.

@article{Alcaraz2017IonTI,
  title={Ion Transport in Confined Geometries below the Nanoscale: Access Resistance Dominates Protein Channel Conductance in Diluted Solutions.},
  author={Antonio Alcaraz and Mar{\'i}a-Lid{\'o}n Lopez and Mar{\'i}a Queralt-Mart{\'i}n and Vicente M Aguilella},
  journal={ACS nano},
  year={2017},
  volume={11 10},
  pages={10392-10400}
}
Synthetic nanopores and mesoscopic protein channels have common traits like the importance of electrostatic interactions between the permeating ions and the nanochannel. Ion transport at the nanoscale occurs under confinement conditions so that the usual assumptions made in microfluidics are challenged, among others, by interfacial effects such as access resistance (AR). Here, we show that a sound interpretation of electrophysiological measurements in terms of channel ion selective properties… CONTINUE READING