Ion Channels and Synaptic Organization Analysis of the Drosophila Genome

@article{Littleton2000IonCA,
  title={Ion Channels and Synaptic Organization Analysis of the Drosophila Genome},
  author={J. Littleton and B. Ganetzky},
  journal={Neuron},
  year={2000},
  volume={26},
  pages={35-43}
}
  • J. Littleton, B. Ganetzky
  • Published 2000
  • Biology, Medicine
  • Neuron
  • The most obvious conclusion from this survey is that neuronal signaling proteins, for the most part, have been highly conserved throughout evolution. Despite the dramatic differences in complexity and organization of nervous systems and behavioral outputs in worms, flies, and mammals, the key proteins, and presumably the functional mechanisms they govern, are remarkably similar. Apparently, the basic framework for neuronal signaling and synaptic organization was completed early in metazoan… CONTINUE READING
    443 Citations
    Neurobiology and the Drosophila genome
    • 38
    Evolution tunes the excitability of individual neurons
    • 45
    • PDF
    A Post-Synaptic Scaffold at the Origin of the Animal Kingdom
    • 267
    • PDF
    Potassium channels in C. elegans.
    • 54
    • PDF
    Genetic analysis of nicotinic signaling in worms and flies.
    • W. Schafer
    • Biology, Medicine
    • Journal of neurobiology
    • 2002
    • 12
    • PDF
    Analysis of functional neuronal connectivity in the Drosophila brain.
    • 85
    • PDF
    The genetic analysis of functional connectomics in Drosophila.
    • 28

    References

    SHOWING 1-10 OF 38 REFERENCES
    BEHAVIORAL MUTANTS OF Drosophila ISOLATED BY COUNTERCURRENT DISTRIBUTION.
    • S. Benzer
    • Biology, Medicine
    • Proceedings of the National Academy of Sciences of the United States of America
    • 1967
    • 615
    • PDF
    Ion channels in Drosophila.
    • 40
    Neurogenetic studies of ion channels in Drosophila.
    • 85
    The Drosophila erg K+ Channel Polypeptide Is Encoded by the Seizure Locus
    • 109
    • PDF
    The genome sequence of Drosophila melanogaster.
    • 5,802
    • PDF
    Signal transduction in the Caenorhabditis elegans nervous system.
    • 152
    RNA editing in the Drosophila DMCA1A calcium-channel alpha 1 subunit transcript.
    • 53
    Comparative genomics of the eukaryotes.
    • 1,060
    • PDF