• DOI:10.1016/S0896-6273(00)81135-6
Corpus ID: 5694563

Ion Channels and Synaptic Organization Analysis of the Drosophila Genome

@article{Littleton2000IonCA,
  title={Ion Channels and Synaptic Organization Analysis of the Drosophila Genome},
  author={J. Littleton and B. Ganetzky},
  journal={Neuron},
  year={2000},
  volume={26},
  pages={35-43}
}

J. Littleton, B. Ganetzky

Published 2000

Biology, Medicine

Neuron

The most obvious conclusion from this survey is that neuronal signaling proteins, for the most part, have been highly conserved throughout evolution. Despite the dramatic differences in complexity and organization of nervous systems and behavioral outputs in worms, flies, and mammals, the key proteins, and presumably the functional mechanisms they govern, are remarkably similar. Apparently, the basic framework for neuronal signaling and synaptic organization was completed early in metazoan… CONTINUE READING

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