Iodised rapeseed oil for eradication of severe endemic goitre

@article{Ingenbleek1997IodisedRO,
  title={Iodised rapeseed oil for eradication of severe endemic goitre},
  author={Y. Ingenbleek and L. Jung and G. F{\'e}rard and F. Bordet and L. Dechoux and A. Gonçalves},
  journal={The Lancet},
  year={1997},
  volume={350},
  pages={1542-1545}
}
Iodised oil is traditionally based on the fatty acids (FAs) of the poppyseed, an expensive commodity. An equipotent but cheaper vehicle would be welcome. Iodination of rapeseed oil yields a product (Brassiodol) with a total iodine content of 376 mg/mL. Brassiodol has been compared with the poppyseed-based Lipiodol in two villages in Chad in the west African goitre belt. A 2 mL dose of Brassiodol is followed by urinary spillover of half the ingested iodine. The other half undergoes tissue… Expand
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References

SHOWING 1-10 OF 26 REFERENCES
New model for describing urinary iodine excretion: its use for comparing different oral preparations of iodized oil.
TLDR
A hyperbolic function was found to describe changes in urinary iodine concentration over time more adequately than a simple exponential function in a study comparing different treatments of severely iodine-deficient schoolchildren from Malawi. Expand
Prevalence of iodine deficiency disorders and goitre in Chad
TLDR
A nationwide sample survey was conducted in Chad to establish the prevalence of iodine deficiency disorders (IDD) and females had goitre significantly more often, and cretinism varied between o and 1.2%, and was highest in the Sahel zone. Expand
PROGRESS IN THE PREVENTION AND CONTROL OF IODINE-DEFICIENCY DISORDERS
TLDR
The regional data give relat ively good Information conceming the populat ion sample studied; however, it is frequently dif f icult to conclude which part of the total population of a given area is represented by the sample studied and what percent of thetotal inhabitants of the country l ive in the areas studied. Expand
The disorders induced by iodine deficiency.
  • F. Delange
  • Medicine
  • Thyroid : official journal of the American Thyroid Association
  • 1994
TLDR
Iodine deficiency constitutes one of the most common preventable causes of mental deficiency in the world today and most of the affected populations live in mountainous areas in preindustrialized countries, but 50 to 100 million people are still at risk in Europe. Expand
Esters of fatty acids iodine, iodine fatty acids and their derivatives, obtained by iodohydrination involving alkylsilyl derivatives with alkali and their pharmacological activities iodides
Iodinated fatty acid esters, iodinated fatty acids and fluid pharmaceutical-grade stable derivatives thereof are produced by iodohydrination in an organic medium using alkylsilylated derivatives,Expand
Iodine deficiency in Europe: a continuing concern.
TLDR
Iodine Nutrition in Individual European Countries: Current Research in Iodine Deficiency in Europe. Expand
Effect of iodine deficiency and cold exposure on thyroxine 5'-deiodinase activity in various rat tissues.
TLDR
It is likely that increased thyroxine (T4)-to-T3 conversion in the greatly enlarged thyroids of LID rats contributed to the maintenance of serum T3, and the inability to demonstrate an increase in uncoupling protein mRNA levels in BAT in response to cold makes it unlikely that BAT contributes to maintenance of Serum T3 in LID Rats. Expand
Selectivity of fatty acid mobilization: a general metabolic feature of adipose tissue.
TLDR
Under conditions of stimulated lipolysis, the selectivity of fatty acid mobilization is a general metabolic feature of adipose tissue and is a metabolic feature common to all adipose tissues. Expand
Micro determination of iodine by a catalytic method
SummaryA procedure is described for the determination of quantities of iodide of the order of 0,05 to 3γ in 1 ml. solution or in a suitable amount of solid sample (sodium chloride). The method isExpand
PREVENTION OF SIMPLE GOITER IN MAN: FOURTH PAPER
TLDR
The present paper deals with the data obtained at the fourth general examination made October 13-17, 1919, together with summaries and conclusions based on observations extending over a period of thirty months. Expand
...
1
2
3
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