Iodine-123-4-amino-3-iodobenzylguanidine, a new sympathoadrenal imaging agent: comparison with iodine-123 metaiodobenzylguanidine.

  title={Iodine-123-4-amino-3-iodobenzylguanidine, a new sympathoadrenal imaging agent: comparison with iodine-123 metaiodobenzylguanidine.},
  author={Barry L. Shulkin and Brahm Shapiro and Michael C. Tobes and S W Shen and Donald M. Wieland and Lawrence Meyers and Heewon Lee and Neil A. Petry and James Sisson and William H. Beierwaltes},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  volume={27 7},
Iodine-123-4-amino-3-iodobenzylguanidine ([123I]AIBG), an analog of 123I metaiodobenzylguanidine ([123I]MIBG), has an advantage in having a more rapid and simple synthesis. This, combined with animal data that suggested a greater affinity of the new radiopharmaceutical for the autonomic innervation of the myocardium led us to study the biodistribution of [123I]AIBG in three men with metastatic pheochromocytoma. In all instances, [123I]AIBG revealed the same metastatic deposits shown by [123I… CONTINUE READING


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