Iodide handling by the thyroid epithelial cell.

@article{Nilsson2001IodideHB,
  title={Iodide handling by the thyroid epithelial cell.},
  author={Michael J Nilsson},
  journal={Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association},
  year={2001},
  volume={109 1},
  pages={13-7}
}
Iodination of thyroglobulin, the key event in the synthesis of thyroid hormone, is an extracellular process that takes place inside the thyroid follicles at the apical membrane surface that faces the follicular lumen. The supply of iodide involves two steps of TSH-regulated transport, basolateral uptake and apical efflux, that imprint the polarized phenotype of the thyroid cell. Iodide uptake is generated by the sodium/iodide symporter present in the basolateral plasma membrane. A candidate for… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 22 extracted citations

Further characterisation of the recently described SLC26A4 c.918+2T>C mutation and reporting of a novel variant predicted to be damaging

Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale • 2016
View 2 Excerpts

Thyroid Examination in Low-Radiation Exposed Iraqi Clean-up Workers — Immunogenetic Study

Mithal Abdulkareem Abd Oun, Amina Naama AL-Thwani, Saad Hussein Khudaier, Laith Abd al-elah, Kamel
2013
View 1 Excerpt

Similar Papers

Loading similar papers…