Inward rectifiers in the heart: an update on I(K1).


The cardiac inward rectifier potassium current (I(K1)), present in all ventricular and atrial myocytes, has been suggested to play a major role in repolarization of the action potential and stabilization of the resting potential. The molecular basis is now ascribed to members of the Kir2 sub-family of inward rectifier K channel genes, and the availability… (More)