Inward calcium currents in cultured and freshly isolated detrusor muscle cells: evidence of a T-type calcium current.

@article{Sui2001InwardCC,
  title={Inward calcium currents in cultured and freshly isolated detrusor muscle cells: evidence of a T-type calcium current.},
  author={G. P. Sui and Clara Hoi Ka Wu and Christopher Henry Fry},
  journal={The Journal of urology},
  year={2001},
  volume={165 2},
  pages={621-6}
}
PURPOSE We carefully examined the possible routes of Ca2+ influx, and determined whether cultured cells retain Ca2+ channels and whether the culturing process changes their properties. MATERIALS AND METHODS Inward currents were measured under voltage clamp in freshly isolated cells and myocytes from confluent cell cultures of detrusor smooth muscle. RESULTS In guinea pig and human cells mean peak inward current density plus or minus standard deviation decreased significantly in cell culture… CONTINUE READING
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