Involvement of thyroid hormone and its alpha receptor in avian neurulation.

  title={Involvement of thyroid hormone and its alpha receptor in avian neurulation.},
  author={Fr{\'e}d{\'e}ric Flamant and Jacques Samarut},
  journal={Developmental biology},
  volume={197 1},
We have analyzed the expression pattern of c-erb A alpha and c-erb A beta which encode the thyroid hormone receptors (T3R alpha and T3R beta) during early chicken embryogenesis. Only c-erb A alpha expression was detected by RT-PCR and whole-mount in situ hybridization. c-erb A alpha transcripts were found to be already present at low level in embryos before egg incubation. During neurulation a marked increase was observed in neurectoderm. A reporter cell line was then constructed and used to… CONTINUE READING


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