Involvement of the ventral tegmental area (VTA) in morphine-induced memory retention in morphine-sensitized rats.

@article{Zarrindast2005InvolvementOT,
  title={Involvement of the ventral tegmental area (VTA) in morphine-induced memory retention in morphine-sensitized rats.},
  author={Mohammad Reza Zarrindast and Zahra Farajzadeh and Parvin Rostami and Ameneh Rezayof and Parvaneh Nourjah},
  journal={Behavioural brain research},
  year={2005},
  volume={163 1},
  pages={100-6}
}
In the present study, the effects of intra-ventral tegmental area (VTA) injections of morphine on memory retention of a one-trial passive avoidance task have been investigated in morphine-sensitized rats. Retrieval was examined 24h after training and used as memory retention. Sensitization was obtained by subcutaneous (s.c.) injections of morphine, once daily for 3 and 5 days free of the opioid before training. Post-training administration of the both systemic (2.5, 5 and 7.5mg/kg, s.c.) and… CONTINUE READING