Involvement of the sympathetic nervous system in complex regional pain syndrome.

@article{Drummond2004InvolvementOT,
  title={Involvement of the sympathetic nervous system in complex regional pain syndrome.},
  author={Peter D. Drummond},
  journal={The international journal of lower extremity wounds},
  year={2004},
  volume={3 1},
  pages={35-42}
}
Complex regional pain syndrome (CRPS) occasionally develops as a complication of limb trauma. Sympathetic neurotransmitter release is compromised in the affected limb of at least a subgroup of patients throughout the course of the disorder, whereas signs of sympathetic deficit (a warm flushed limb) often evolve into signs of sympathetic overactivity (a cool moist limb) due to the development of adrenergic supersensitivity. Cross-talk between sympathetic neurotransmitters and the sensory neurons… CONTINUE READING
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