Involvement of the melanocortin MC4 receptor in stress-related behavior in rodents.

@article{Chaki2003InvolvementOT,
  title={Involvement of the melanocortin MC4 receptor in stress-related behavior in rodents.},
  author={Shigeyuki Chaki and Shin-ichi Ogawa and Yoshihisa Toda and Takeo Funakoshi and Shigeru Okuyama},
  journal={European journal of pharmacology},
  year={2003},
  volume={474 1},
  pages={95-101}
}
The melanocortin subtype 4 (MC4) receptor has been postulated to be involved in stress and stress-related behavior. We made use of melanocortin MC4 receptor agonists and antagonist to investigate the relationship between the melanocortin MC4 receptor and stress related disorders. The nonspecific melanocortin receptor agonist alpha-melanocyte stimulating hormone (alpha-MSH) and the melanocortin MC4 receptor agonist, Ac-[Nle4,Asp5,D-Phe7,Lys10]alpha-MSH-(4-10)-NH2 (MT II) dose-dependently and… CONTINUE READING

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