Involvement of the insular cortex in the consolidation and expression of contextual fear conditioning.

@article{Alves2013InvolvementOT,
  title={Involvement of the insular cortex in the consolidation and expression of contextual fear conditioning.},
  author={Fernando H F Alves and Felipe Villela Gomes and Daniel Gustavo dos Reis and Carlos C Crestani and Fernando M. A. Corr{\^e}a and Francisco S Guimar{\~a}es and Leonardo B. M. Resstel},
  journal={The European journal of neuroscience},
  year={2013},
  volume={38 2},
  pages={2300-7}
}
The insular cortex (IC) has been reported to be involved in the modulation of memory and autonomic and defensive responses. However, there is conflicting evidence about the role of the IC in fear conditioning. To explore the IC involvement in both behavioral and autonomic responses induced by contextual fear conditioning, we evaluated the effects of the reversible inhibition of the IC neurotransmission through bilateral microinjections of the non-selective synapse blocker CoCl2 (1 mm) 10 min… CONTINUE READING
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