Involvement of the human pedunculopontine nucleus region in voluntary movements.

  title={Involvement of the human pedunculopontine nucleus region in voluntary movements.},
  author={Eric W. K. Tsang and Clement Hamani and Elena Moro and Filomena Mazzella and Yu Yan Poon and Andres M. Lozano and R Chen},
  volume={75 11},
OBJECTIVE The pedunculopontine nucleus region (PPNR) is being investigated as a target for deep brain stimulation (DBS) in Parkinson disease (PD), particularly for gait and postural impairment. A greater understanding of how PPNR activities and oscillations are modulated with voluntary movements is crucial to the development of neuromodulation strategies. METHODS We studied 7 patients with PD who underwent DBS electrode implantations in the PPNR. PPNR local field potential and EEG were… CONTINUE READING
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