Involvement of the brain histaminergic system in addiction and addiction-related behaviors: A comprehensive review with emphasis on the potential therapeutic use of histaminergic compounds in drug dependence

@article{Brabant2010InvolvementOT,
  title={Involvement of the brain histaminergic system in addiction and addiction-related behaviors: A comprehensive review with emphasis on the potential therapeutic use of histaminergic compounds in drug dependence},
  author={Christian Brabant and Livia Alleva and Etienne Quertemont and Ezio Tirelli},
  journal={Progress in Neurobiology},
  year={2010},
  volume={92},
  pages={421-441}
}
Neurons that produce histamine are exclusively located in the tuberomamillary nucleus of the posterior hypothalamus and send widespread projections to almost all brain areas. Neuronal histamine is involved in many physiological and behavioral functions such as arousal, feeding behavior and learning. Although conflicting data have been published, several studies have also demonstrated a role of histamine in the psychomotor and rewarding effects of addictive drugs. Pharmacological and brain… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 19 extracted citations