Involvement of the Neutral Amino Acid Transporter SLC6A15 and Leucine in Obesity-Related Phenotypes

@inproceedings{Drgonov2013InvolvementOT,
  title={Involvement of the Neutral Amino Acid Transporter SLC6A15 and Leucine in Obesity-Related Phenotypes},
  author={Jana Drgonov{\'a} and Josefin A. Jacobsson and Joan C. Han and Jack A. Yanovski and Robert Fredriksson and Claude Marcus and Helgi B. Schi{\"o}th and George R. Uhl},
  booktitle={PloS one},
  year={2013}
}
Brain pathways, including those in hypothalamus and nucleus of the solitary tract, influence food intake, nutrient preferences, metabolism and development of obesity in ways that often differ between males and females. Branched chain amino acids, including leucine, can suppress food intake, alter metabolism and change vulnerability to obesity. The SLC6A15 (v7-3) gene encodes a sodium-dependent transporter of leucine and other branched chain amino acids that is expressed by neurons in… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 10 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 54 REFERENCES

The

  • MA Kohli, S Lucae, PG Saemann, MV Schmidt, A Demirkan
  • neuronal
  • 2011

Similar Papers

Loading similar papers…