Involvement of the Cannabinoid CB1 Receptor in Modulation of Dopamine Output in the Prefrontal Cortex Associated with Food Restriction in Rats

@inproceedings{Dazzi2014InvolvementOT,
  title={Involvement of the Cannabinoid CB1 Receptor in Modulation of Dopamine Output in the Prefrontal Cortex Associated with Food Restriction in Rats},
  author={Laura Dazzi and Giuseppe Talani and Francesca Biggio and Cinzia Utzeri and Valeria Lallai and Valentina Licheri and Stefano Lutzu and Maria Cristina Mostallino and Pietro Paolo Secci and Giovanni Biggio and Enrico Sanna},
  booktitle={PloS one},
  year={2014}
}
Increase in dopamine output on corticolimbic structures, such as medial prefrontal cortex (mPFC) and nucleus accumbens, has been related to reward effects associated with palatable food or food presentation after a fasting period. The endocannabinoid system regulates feeding behavior through a modulatory action on different neurotransmitter systems, including the dopaminergic system. To elucidate the involvement of type 1 cannabinoid receptors in the regulation of dopamine output in the mPFC… CONTINUE READING