Involvement of the Azotobacter vinelandii Rhodanese-Like Protein RhdA in the Glutathione Regeneration Pathway

@inproceedings{Remelli2012InvolvementOT,
  title={Involvement of the Azotobacter vinelandii Rhodanese-Like Protein RhdA in the Glutathione Regeneration Pathway},
  author={William Remelli and Nicoletta Guerrieri and Jennifer Klodmann and Jutta Papenbrock and Silvia M. C. Pagani and Fabio Forlani},
  booktitle={PloS one},
  year={2012}
}
The phenotypic features of the Azotobacter vinelandii RhdA mutant MV474 (in which the rhdA gene was deleted) indicated that defects in antioxidant systems in this organism were related to the expression of the tandem-domain rhodanese RhdA. In this work, further insights on the effects of the oxidative imbalance generated by the absence of RhdA (e.g. increased levels of lipid hydroperoxides) are provided. Starting from the evidence that glutathione was depleted in MV474, and using both in silico… CONTINUE READING
6 Citations
47 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 47 references

Significance of the intramolecular transformation of glutathione thiyl radicals to a-aminoalkyl radicals. Thermochemical and biological implications

  • R Zhao, J Lind, G Merenyi, T E. Eriksen
  • J Chem Soc, Perkin Trans
  • 1997
Highly Influential
4 Excerpts

Reactions of thiyl radicals

  • P Wardman
  • 1995
Highly Influential
4 Excerpts

Similar Papers

Loading similar papers…