Involvement of the δ-opioid receptor in exercise-induced cardioprotection.

  title={Involvement of the δ-opioid receptor in exercise-induced cardioprotection.},
  author={Lindsey E Miller and Graham Mcginnis and Bridget Ayuk Peters and Christopher G. Ballmann and Gayani Nanayakkara and Rajesh H Amin and John C Quindry},
  journal={Experimental physiology},
  volume={100 4},
NEW FINDINGS What is the central question of this study? Does the δ-opioid receptor trigger exercise-induced cardioprotection against ischaemia-reperfusion injury? What is the main finding and its importance? In exercised hearts, the δ-opioid receptor appears to trigger cardioprotection against ischaemia-reperfusion-induced tissue necrosis but not apoptosis. ABSTRACT Endogenous opioids mediate exercise-induced cardioprotection against ischaemia-reperfusion (IR) injury, although the opioid… CONTINUE READING
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