Involvement of sigma-1 receptor in astrocyte activation induced by methamphetamine via up-regulation of its own expression

Abstract

Although it has been documented that methamphetamine induces astrocyte activation, the mechanism(s) underlying this effect remain poorly understood. We thus sought to examine the molecular mechanisms involved in methamphetamine-mediated activation of astrocytes with a focus on the role of sigma-1 receptor (σ-1R) in this process. The expression of σ-1R and… (More)
DOI: 10.1186/s12974-015-0250-7

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@inproceedings{Zhang2015InvolvementOS, title={Involvement of sigma-1 receptor in astrocyte activation induced by methamphetamine via up-regulation of its own expression}, author={Yuan Ting Zhang and Xuan Lv and Ying Bai and Xinjian Zhu and Xiaodong Wu and Jie Chao and Ming Duan and Shilpa Buch and Ling Chen and Honghong Yao}, booktitle={Journal of Neuroinflammation}, year={2015} }