Involvement of progesterone receptors in ascorbic acid-mediated protection against ischemia-reperfusion-induced acute kidney injury.

@article{Sandhi2014InvolvementOP,
  title={Involvement of progesterone receptors in ascorbic acid-mediated protection against ischemia-reperfusion-induced acute kidney injury.},
  author={Jasmine Sandhi and J. Singh and T. Kaur and S. Ghuman and A. Singh},
  journal={The Journal of surgical research},
  year={2014},
  volume={187 1},
  pages={
          278-88
        }
}
  • Jasmine Sandhi, J. Singh, +2 authors A. Singh
  • Published 2014
  • Medicine
  • The Journal of surgical research
  • BACKGROUND Ascorbic acid (AA) is an established antioxidant and has been used for treatment of various disorders. Recent reports suggest that administration of AA increases the level of steroids such as progesterone in the body. The present study investigated the protective role of progesterone against ischemia-reperfusion-induced acute kidney injury (AKI) and possible involvement of progesterone receptors in AA-mediated renoprotection in rats. MATERIALS AND METHODS The male rats were… CONTINUE READING
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