Involvement of polyamines in apoptosis of cardiac myoblasts in a model of simulated ischemia.

@article{Tantini2006InvolvementOP,
  title={Involvement of polyamines in apoptosis of cardiac myoblasts in a model of simulated ischemia.},
  author={Benedetta Tantini and Emanuela Fiumana and Silvia Cetrullo and Carla Pignatti and Francesca Bonavita and Lisa M. Shantz and Emanuele Giordano and Claudio Muscari and Flavio Flamigni and C. Richard Guarnieri and Claudio Stefanelli and Claudio Marcello Caldarera},
  journal={Journal of molecular and cellular cardiology},
  year={2006},
  volume={40 6},
  pages={775-82}
}
Apoptotic cell death of cardiomyocytes is involved in several cardiovascular diseases including ischemia, hypertrophy, and heart failure. The polyamines putrescine, spermidine, and spermine are polycations absolutely required for cell growth and division. However, increasing evidence indicates that polyamines, cell growth, and cell death can be tightly connected. In this paper, we have studied the involvement of polyamines in apoptosis of H9c2 cardiomyoblasts in a model of simulated ischemia… CONTINUE READING

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