Involvement of parental imprinting in the antisense regulation of onco-miR-372-373.

Abstract

The monoallelic nature of imprinted genes renders them highly susceptible to genetic and epigenetic perturbations, potentially resulting in transformation and disease. Here we show, using parthenogenetic induced pluripotent stem cells, an imprinted transcript that serves as an antisense regulator of onco-miR-372-3 (named anti-miR-371-3). As miR-372-3 have… (More)
DOI: 10.1038/ncomms3724

Topics

7 Figures and Tables

Cite this paper

@article{Stelzer2013InvolvementOP, title={Involvement of parental imprinting in the antisense regulation of onco-miR-372-373.}, author={Yonatan Stelzer and Ido Sagi and Nissim Benvenisty}, journal={Nature communications}, year={2013}, volume={4}, pages={2724} }