Involvement of oxidative stress and caspase-3 in cortical infarction after photothrombotic ischemia in mice.

@article{Kim2000InvolvementOO,
  title={Involvement of oxidative stress and caspase-3 in cortical infarction after photothrombotic ischemia in mice.},
  author={Gyung Whan Kim and Taku Sugawara and Pak Hoo Chan},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year={2000},
  volume={20 12},
  pages={1690-701}
}
Apoptosis-related cell death is linked to oxidative stress and caspases in experimental cerebral ischemia. However, the role of oxidative stress in caspase activation and subsequent apoptotic cell death after cerebral ischemia is unknown. The authors evaluated the role of oxidative stress in ischemic cerebral infarction after photothrombosis and the relation between oxidative stress and caspase-related cell death 6 and 24 hours after ischemia with and without U-74389G, a potent free radical… CONTINUE READING

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