Involvement of orexinergic receptors in the nucleus accumbens, in the effect of forced swim stress on the reinstatement of morphine seeking behaviors

@article{Farzinpour2019InvolvementOO,
  title={Involvement of orexinergic receptors in the nucleus accumbens, in the effect of forced swim stress on the reinstatement of morphine seeking behaviors},
  author={Zahra Farzinpour and Zahra Taslimi and Ronak Azizbeigi and Saeideh Karimi-Haghighi and Abbas Haghparast},
  journal={Behavioural Brain Research},
  year={2019},
  volume={356},
  pages={279-287}
}
Orexinergic system is involved in primary rewards; the neural circuit of the ventral tegmental area (VTA), nucleus accumbens (NAc), prefrontal cortex and amygdala represents overlapping elements mediating the rewarding effects of drugs and stressful experiences. The NAc integrates reward-related information from the VTA. Also, it has been indicated that orexinergic system activates the mesolimbic dopamine projecting neurons to the NAc and promotes the development of reward in rodents. Therefore… CONTINUE READING

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