Involvement of norepinephrine and serotonin system in antidepressant-like effects of hederagenin in the rat model of unpredictable chronic mild stress-induced depression.

Abstract

CONTEXT Previous studies from our laboratory indicated that both acute and subchronic administration of Fructus Akebiae (FAE) [the fruit of Akebiae quinata (Thunb.) Decne, (Lardizabalaceae)] produce antidepressant-like effects in animal depressive behavior tests. FAE contains approximately 70% of hederagenin (HG) as its main chemical component. OBJECTIVE… (More)
DOI: 10.3109/13880209.2014.922586

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@article{Liang2015InvolvementON, title={Involvement of norepinephrine and serotonin system in antidepressant-like effects of hederagenin in the rat model of unpredictable chronic mild stress-induced depression.}, author={Bao-Fang Liang and Fang Huang and Hai-Tao Wang and Guo-hua Wang and Xin Yuan and Ming-zi Zhang and Hai-Biao Guo and Yu-Fang Cheng and Jiangping Xu}, journal={Pharmaceutical biology}, year={2015}, volume={53 3}, pages={368-77} }