Involvement of nitric oxide in the reflex relaxation of the stomach to accommodate food or fluid

@article{Desai1991InvolvementON,
  title={Involvement of nitric oxide in the reflex relaxation of the stomach to accommodate food or fluid},
  author={Ketan M. Desai and William C Sessa and John R. Vane},
  journal={Nature},
  year={1991},
  volume={351},
  pages={477-479}
}
THE fundus of the guinea-pig stomach actively dilates in response to low increases in intragastric pressure1. This physiological response, now called adaptive relaxation2,3, accommodates the intake of liquid or food. It is independent of external innervation, resistant to ganglion blockade, but reflex in origin. The nerves involved are neither adrenergic nor cholinergic in nature. Non-adrenergic, non-cholinergic (NANC) nerves have now been recognized in many parts of the gastrointestinal tract4… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 136 extracted citations

High K+-Induced Relaxation by Nitric Oxide in Human Gastric Fundus

The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology • 2012
View 4 Excerpts
Highly Influenced

Nitric Oxide-mediated Relaxation by High K+ in Human Gastric Longitudinal Smooth Muscle

The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology • 2011
View 4 Excerpts
Highly Influenced

Gastrointestinal function regulation by nitrergic efferent nerves.

Pharmacological reviews • 2005
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…