Involvement of nitric oxide in permeability alteration and F-actin redistribution induced by phorbol myristate acetate in endothelial cells.

Abstract

We have previously reported that phorbol myristate acetate (PMA) caused a decrease in endothelial permeability during the first 1 to 1.5 h of exposure and thereafter an increase for up to 6 h. This permeability alteration was correlated with a time-dependent redistribution of F-actin, i.e., an increase in dense peripheral bands was observed during the first… (More)

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