Involvement of neuronal IL-1β in acquired brain lesions in a rat model of neonatal encephalopathy

@inproceedings{Savard2013InvolvementON,
  title={Involvement of neuronal IL-1β in acquired brain lesions in a rat model of neonatal encephalopathy},
  author={Alexandre Savard and Karine Lavoie and Marie-Elsa Brochu and Djordje M Grbic and Martin Lepage and Denis Gris and Guillaume Sebire},
  booktitle={Journal of Neuroinflammation},
  year={2013}
}
Infection-inflammation combined with hypoxia-ischemia (HI) is the most prevalent pathological scenario involved in perinatal brain damage leading to life-long neurological disabilities. Following lipopolysaccharide (LPS) and/or HI aggression, different patterns of inflammatory responses have been uncovered according to the brain differentiation stage [Brochu et al.: J Neuroinflammation 8:55, 2011]. In fact, LPS pre-exposure has been reported to aggravate HI brain lesions in post-natal day 1 (P1… CONTINUE READING
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