Involvement of mytilins in mussel antimicrobial defense.

  title={Involvement of mytilins in mussel antimicrobial defense.},
  author={Guillaume Mitta and Franck Vandenbulcke and François No{\"e}l Hubert and Michel Salzet and Philippe Roch},
  journal={The Journal of biological chemistry},
  volume={275 17},
Four cationic peptides were purified from mussel (Mytilus galloprovincialis) hemocytes. A combination of Edman degradation and mass spectrometry of plasma revealed (i) a previously characterized molecule, mytilin B (Charlet, M., Chernysh, S., Philippe, H., Hetrut, C., Hoffmann, J., and Bulet, P. (1996) J. Biol. Chem. 271, 21808-21813) and (ii) three new isoforms, mytilin C, D, and G1. The four molecules exhibited complementary antimicrobial properties. The cDNA sequence coding for the mytilin B… CONTINUE READING


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