Involvement of myosin Vb in glutamate receptor trafficking.

  title={Involvement of myosin Vb in glutamate receptor trafficking.},
  author={Marie-France Lis{\'e} and Tak Pan Wong and Alex Trinh and Rochelle M Hines and Lidong Liu and Rujun Kang and Dustin J Hines and Jie Lu and James R Goldenring and Yu Tian Wang and Alaa El Din El-Husseini},
  journal={The Journal of biological chemistry},
  volume={281 6},
Myosin V motors mediate cargo transport; however, the identity of neuronal molecules transported by these proteins remains unknown. Here we show that myosin Vb is expressed in several neuronal populations and associates with the alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate-type glutamate receptor subunit GluR1. In developing hippocampal neurons, expression of the tail domain of myosin Vb, but not myosin Va, enhanced GluR1 accumulation in the soma and reduced its surface expression… CONTINUE READING


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Myosin Vb Role in Glutamate Receptor Trafficking 3678 JOURNAL OF BIOLOGICAL CHEMISTRY

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