Involvement of multidrug resistance-associated protein 2 (ABCC2/Mrp2) in biliary excretion of micafungin in rats.

Abstract

The drug transporter, multidrug resistance-associated protein 2 (ABCC2/Mrp2), is known to play important roles in excretion of various drugs. In the present study, we investigated whether Mrp2 is involved in the transport of micafungin, a newly developed antifungal agent. When Sprague-Dawley rats received an intravenous injection of micafungin (1 mg/kg) in… (More)
DOI: 10.1016/j.lfs.2008.06.013

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@article{Abe2008InvolvementOM, title={Involvement of multidrug resistance-associated protein 2 (ABCC2/Mrp2) in biliary excretion of micafungin in rats.}, author={Fumie Abe and Jun Ueyama and Akiko Kimata and Miki Kato and Tamon Hayashi and Masayuki Nadai and Hiroko Saito and Naoshi Takeyama and Hiroshi Noguchi and Takaaki Hasegawa}, journal={Life sciences}, year={2008}, volume={83 7-8}, pages={229-35} }