Involvement of mitochondrial dysfunction in the adverse effect exerted by seminal plasma from men with spinal cord injury on sperm motility.

@article{Barbonetti2013InvolvementOM,
  title={Involvement of mitochondrial dysfunction in the adverse effect exerted by seminal plasma from men with spinal cord injury on sperm motility.},
  author={Arcangelo Barbonetti and Maria Rosaria Caterina Vassallo and Alessandra Di Rosa and Y Leombruni and Giorgio Felzani and Loredana Gandini and Andrea Lenzi and Stefano Necozione and Sandro Francavilla and Felice Francavilla},
  journal={Andrology},
  year={2013},
  volume={1 3},
  pages={456-63}
}
The aetiology of severe asthenozoospermia in men with spinal cord injury includes an adverse impact of seminal plasma (SP) on sperm motility. In this study we investigated the effect exerted by SP from men with SCI on donor sperm mitochondrial activity and its reflection on motility. Donor spermatozoa were exposed (1 h) to SP from 22 ejaculates of men with SCI. Only SP from samples exhibiting both a low fructose level and an inhibitory effect on mitochondrial membrane potential (ΔΨm), assessed… CONTINUE READING

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