Involvement of lactate in glucose metabolism and glucosensing function in selected tissues of rainbow trout.

@article{Polakof2008InvolvementOL,
  title={Involvement of lactate in glucose metabolism and glucosensing function in selected tissues of rainbow trout.},
  author={Sergio Polakof and Jos{\'e} L Soengas},
  journal={The Journal of experimental biology},
  year={2008},
  volume={211 Pt 7},
  pages={1075-86}
}
The aim of this study was to obtain evidence in rainbow trout for a role of lactate in glucose homeostasis as well as in the function of glucosensing tissues. In a first set of experiments, trout were injected, either (1) intraperitoneally (N=8) with 5 ml kg(-1) of Cortland saline alone (control) or saline containing l-(+)-lactate (22.5 mg kg(-1) or 45 mg kg(-1)), oxamate (22.5 mg kg(-1)) or d-glucose (500 mg kg(-1)), or (2) intracerebroventricularly (N=11) with 1 microl 100 g(-1) body mass of… CONTINUE READING
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