Involvement of kappa-opioids in the mouse cerebellar adenosinergic modulation of ethanol-induced motor incoordination.

@article{Dar1998InvolvementOK,
  title={Involvement of kappa-opioids in the mouse cerebellar adenosinergic modulation of ethanol-induced motor incoordination.},
  author={Moahad S. Dar},
  journal={Alcoholism, clinical and experimental research},
  year={1998},
  volume={22 2},
  pages={444-54}
}
  • Moahad S. Dar
  • Published 1998 in Alcoholism, clinical and experimental research
Using rotorod performance as the test response, possible modulation and co-modulation of ethanol-induced motor incoordination by the cerebellar kappa-opioid and adenosine A1 receptors was studied. A dose-related accentuation of ethanol-induced motor incoordination was observed after direct cerebellar microinfusion of three kappa-opioid receptor agonists: U-50488, U-62066, and bremazocine. On the contrary, significant and dose-related attenuation of ethanol's motor impairment was produced by… CONTINUE READING

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