Involvement of interleukin-17A-induced expression of heat shock protein 47 in intestinal fibrosis in Crohn's disease.

Abstract

OBJECTIVE Intestinal fibrosis is a clinically important issue in Crohn's disease (CD). Heat shock protein (HSP) 47 is a collagen-specific molecular chaperone involved in fibrotic diseases. The molecular mechanisms of HSP47 induction in intestinal fibrosis related to CD, however, remain unclear. Here we investigated the role of interleukin (IL)-17A-induced… (More)
DOI: 10.1136/gutjnl-2013-305632

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@article{Honzawa2014InvolvementOI, title={Involvement of interleukin-17A-induced expression of heat shock protein 47 in intestinal fibrosis in Crohn's disease.}, author={Yusuke Honzawa and Hiroshi Nakase and Masahiro Shiokawa and Takuya Yoshino and Hirotsugu Imaeda and Minoru Matsuura and Yuzo Kodama and Hiroki Ikeuchi and Akira Andoh and Yoshiharu Sakai and Kazuhiro Nagata and Tsutomu Chiba}, journal={Gut}, year={2014}, volume={63 12}, pages={1902-12} }