Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines.

@article{Meng2006InvolvementOH,
  title={Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines.},
  author={Fanyin Meng and Roger D Henson and Molly Lang and Hania Wehbe and Shail Maheshwari and Joshua T. Mendell and Jinmai Jiang and Thomas D. Schmittgen and Tushar Patel},
  journal={Gastroenterology},
  year={2006},
  volume={130 7},
  pages={2113-29}
}
BACKGROUND & AIMS Micro-RNA (miRNA) are endogenous regulatory RNA molecules that modulate gene expression. Alterations in miRNA expression can contribute to tumor growth by modulating the functional expression of critical genes involved in tumor cell proliferation or survival. Our aims were to identify specific miRNA involved in the regulation of cholangiocarcinoma growth and response to chemotherapy. METHODS miRNA expression in malignant and nonmalignant human cholangiocytes was assessed… CONTINUE READING
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