Involvement of heme components in sterol metabolism ofSaccharomyces cerevisiae

@article{Lorenz2006InvolvementOH,
  title={Involvement of heme components in sterol metabolism ofSaccharomyces cerevisiae},
  author={R. Lorenz and L. Parks},
  journal={Lipids},
  year={2006},
  volume={26},
  pages={598-603}
}
  • R. Lorenz, L. Parks
  • Published 2006
  • Chemistry, Medicine
  • Lipids
    • There is an intimate association between sterol biosynthesis in yeast and aerobicity. Besides the requirement for molecular oxygen for the epoxidation of squalene, cytochrome hemoproteins are involved in demethylation and desaturation steps. Regulatory effects of hemes on sterol formation have been demonstrated using specifically defective mutants of yeast. Heme competency participates in a mechanism whereby wild-type cells are prevented from taking exogenous sterols from the growth media. The… CONTINUE READING
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